The thorny issue of using questionnaires in health claim-targeted RCTs.

Questionnaires are often used in clinical and nutritional research to subjectively evaluate the effect of an intervention on an outcome measure or e.g. to select a study population with specific characteristics from a larger pool of potential study participants. Nevertheless, their thoughtless application in health claim-targeted studies have frequently resulted in EFSA dismissing the outcomes generated by these questionnaires. Validation […] >> read more

NutriClaim to present on Probiotic Claims at Health Claim Conference

During the upcoming 7th International Workshop Nutrition & Health Claims Europe, NutriClaim will shed its light on why, up till now, all health claim submissions for probiotics have received a negative opinion from EFSA. The presentation will focus on art. 13.5 and 14 health claims evaluations, primarily pertaining to gastrointestinal and immune health benefits of probiotics. For the full program: […] >> read more

Will EFSA accept that Bifidobacterium BB-12 really improves immune function?

Recently, Rizzardini et al. (B. J. Nutr. 2011) showed that in a vaccination model in healthy subjects supplementation with either Bifidobacterium BB-12 or Lactobacillus casei 431 resulted in significantly greater mean fold increases in total and vaccine-specific antibody titers. However, the question remains whether the observed and statistically significant differences will also be perceived as physiologically relevant by EFSA in […] >> read more

No deficiency – no claims?

Will health claims be authorized if deficiency is non-existent? EFSA’s recent verdict (Oct. 2010) on a large number of health claims made for vitamins and minerals included a statement that ‘the evidence provided does not establish that inadequate intake of [name nutrient] leading to [name claim] occurs in the general EU population. This statement pertained to all the claims evaluations […] >> read more